In this Guide:

Published by the National Agricultural Library, the Agricola database describes publications and resources encompassing all aspects of agriculture and allied disciplines including: animal science; veterinary science; entomology; plant science; forestry; aquaculture and fisheries; farming, farming systems and crops; agricultural economics; extension and education; food and human nutrition; and earth sciences and environmental sciences. The Bibliography of Agriculture is the print index to the agricultural literature going back to 1942 located on the Shields Library, Third Floor, at call number Z 5071 .U63

NOTE: default UCD Search Type set to Advanced Ovid Search.  IMPORTANT: The largest and most comprehensive agricultural literature database is CAB Abstracts.

UCD’s *most* important database on the biology, ecology, technology and management of marine, freshwater, and brackish water environments and organisms. Database consists of the following subfiles: ASFA 1: Biological Sciences and Living Resources; ASFA 2: Ocean Technology, Policy and Non-Living Resources; ASFA 3: Aquatic Pollution and Environmental Quality; ASFA Aquaculture Abstracts; and ASFA Marine Biotechnology Abstracts.

Coverage: varies by subfile; 1971-present;earlier for selected core titles
Tags: Aquaculture, Biology, Fish Biology, Marine Biology
Related links: ASFA LibGuide [ProQuest] , Setting up Alerts

More than 25 million records in all life science areas, including agriculture, biochemistry, biomedicine, biotechnology, ecology, environmental sciences, genetics, microbiology, plant biology, veterinary medicine & pharmacology, and zoology. Indexes over 6000 journals, serials, books and book chapters, conference proceedings and patents.

Citations and abstracts to the international agricultural literature, including veterinary medicine, human and animal nutrition, forestry, rural development, as well as other related topics such as tourism and human ecology. Covers over 11,000 journals & conference proceedings and selected books in agriculture. Produced by CAB (Commonwealth Agricultural Bureaux) International (CABI) with more than 11.6 million records as of 08/10/2016.

Coverage: 1910-present
Tags: Agriculture, Animals, Ecology, Plants, Science

References and abstracts on nursing, biomedical, allied health and consumer health literature. Also includes health care books, nursing dissertations, selected conference proceedings, standards of practice, educational software, audiovisuals and book chapters, as well as Evidence-Based care sheets. Full text is provided for hundreds of journals, plus legal cases, clinical innovations, critical paths, drug records, research instruments and clinical trials. Includes PreCINAHL as a companion database.

Coverage: -1982
Tags: Allied Health, Forensics, Medicine, Nursing

6

VPN

Embase is a biomedical and pharmacological database containing bibliographic records with citations, abstracts and indexing derived from biomedical articles in peer reviewed journals, and is especially strong in its coverage of drug and pharmaceutical research and conference abstracts.Embase contains over 22 million records spanning 1974-present, with over 1 million records added annually. Each record contains the full bibliographic citation, indexing terms, and codes; and 80% of all citations in Embase include author-written abstracts. The Embase journal collection is international with over 7,500 active peer-reviewed journals more than 90 countries. All MEDLINE records produced by the National Library of Medicine (NLM) are included, as well as over 5 million records not covered in MEDLINE. Broad biomedical scope covering the following areas:

  • Drug therapy and research, including pharmaceutics, pharmacology and toxicology
  • Clinical and experimental (human) medicine
  • Basic biological science relevant to human medicine
  • Biotechnology and biomedical engineering, including medical devices
  • Health policy and management, including pharmacoeconomics
  • Public, occupational and environmental health, including pollution control
  • Veterinary science, dentistry, and nursing
  • Psychiatry and mental health, including substance dependence and abuse
  • Forensic science
  • Alternative and complementary medicine
Coverage: 1974-current (for EMBASE records); 1966-current (for MEDLINE records)
Tags: Allied Health, Medicine, Nursing, Public Health

The ERIC Database indexes and abstracts education and education related journals, studies and reports, with links to full-text studies and reports from 1993 forward.

Coverage: 1966-present
Tags: Education

Citations from scholarly journals, conference proceedings, books, reports, and dissertations in physics, electrical engineering and electronics, computers and control, and information technology.

9

More than 27 million citations and abstracts for articles published in approximately 8,400 journals in medicine, life sciences, health administration, veterinary medicine, nursing, molecular biology and genetics. PubMed is a service of the U.S. National Library of Medicine on the NCBI platform.

PubMed Tutorial & more
Alerts/Automatic Updating Service (Saving & Managing Searches)
NLM Searching PubMed with Mesh tri-fold handout [PDF]
NLM PubMed Basics tri-fold handout [PDF]

Coverage: 1946-present
Tags: Animals, Dentistry, Medicine, Nursing, Veterinary Medicine

PsycINFO is a department of the American Psychological Association (APA). It provides citations to articles in professional journals, conference proceedings, books, reports, dissertations and even important internet sites in psychology and related disciplines, most with abstracts and some citations.

Coverage: 1840-present
Tags: Psychology

Offers access to information in all areas of toxicology, including chemicals and pharmaceuticals, pesticides, environmental pollutants, and mutagens and teratogens. TOXLINE is also part of TOXNET but the ProQuest version of TOXLINE has UC-eLinks which is not enabled in TOXNET.

Coverage: 2000-present
Tags: Forensics, Medicine, Toxicology

Web of Science combines traditional bibliographic searching of journal content across the humanities, social sciences, and natural sciences with broadly interdisciplinary “cited reference” search capabilities.

Quick Reference Guide: Web of Science Core Collection
Saving Your Search & Setting Alerts
Creating Citation Alerts for Current Awareness

Coverage: See above description (varies between 9 indexes)
Tags: Science

Primary database for wildlife researchers. The world’s oldest continuing database of animal biology.  Comprehensive coverage of zoology; including behavior, conservation and environmental science, ecology, evolution, genetics, habitat, marine and freshwater biology, nutrition, parasitology and disease, reproduction, taxonomy and systematics, veterinary studies, zoogeography and fossil records. Especially strong in new species reports and field studies.

Coverage: 1864-present
Tags: Animals, Science

Published by the National Agricultural Library, the Agricola database describes publications and resources encompassing all aspects of agriculture and allied disciplines including: animal science; veterinary science; entomology; plant science; forestry; aquaculture and fisheries; farming, farming systems and crops; agricultural economics; extension and education; food and human nutrition; and earth sciences and environmental sciences. The Bibliography of Agriculture is the print index to the agricultural literature going back to 1942 located on the Shields Library, Third Floor, at call number Z 5071 .U63

NOTE: default UCD Search Type set to Advanced Ovid Search.  IMPORTANT: The largest and most comprehensive agricultural literature database is CAB Abstracts.

2

Bibliography on Alternatives to the Use of Live Vertebrates in Biomedical Research and Testing, National Library of Medicine

3

Site for news, information, discussion, and resources from the field of alternatives to animal testing

Australian and New Zealand Council for the Care of Animals in Research and TeachingMany useful resources including Fact Sheets, Newsletters, and publications.

5

Animal Welfare Information Center
Site for information for improved animal care and use in research, teaching, and testing

6

Center for Alternatives to Animal Testing. Johns Hopkins University

Global resources for the development of replacement, reduction and refinement alternatives for research and testing

7

Fund for the Replacement of Animals in Medical Experiments (UK)Researching alternatives to animal use in research, testing, and education

An information resource for members and staff of institutional animal care and use committees. It is a link archive, organized by menus and submenus, produced by the American Association for Laboratory Animal Science (AALAS).

The Institute of Laboratory Animal Research (ILAR) evaluates and disseminates information on issues related to the scientific, technological, and ethical use of animals and related biological resources in research, testing, and education.

Mouse Model Lists, Inbred Strains of Mice and Rats, Mouse Genome Database, and more.

UCDavis, provides links to internet resources and databases for transgenic and targeted mutation research

12

UK-based National Centre for the Replacement, Refinement & Reduction of Animals in Research, Resources, Microsites, Hubs particularly useful.

NTP Interagency Center for the Evaluation of Alternative Toxicological Methods / Interagency Coordinating Committee on the Validation of Alternative Methods

14

Norwegian Inventory of Alternatives. Norwegian Reference Centre for Laboratory Animal Science and AlternativesDatabase of audiovisuals, computer programs, cd-roms, interactive videos, and other alternatives for use in the biological sciences

From NIH, this tool can be used to search a repository of both intramural and extramural NIH-funded research projects from the past 25 years, and access publications and patents resulting from NIH funding. The system also provides access to research supported by the Centers for Disease Control and Prevention (CDC), the Agency for Healthcare Research and Quality (AHRQ), the Health Resources and Services Administration (HRSA), the Substance Abuse and Mental Health Services Administration (SAMHSA), and the U.S. Department of Veterans Affairs (VA). It retains all of the search capabilities of the former CRISP system, while providing additional query fields, hit lists that can be sorted and downloaded to Excel, NIH funding for each project (expenditures), and the publications and patents that have acknowledged support from each project (results).The results of the query are returned in a project listing that includes the project number, subproject identifier (if applicable), project title, contact principal investigator, performing organization, fiscal year of funding, NIH administering and funding Institutes and Centers (IC), and the fiscal year total costs provided by each funding IC. The project number, subproject id, and the project title are clickable and linked to more detailed information on several Project Information tabs, including Description, Details, Results, and Subprojects (for multi-project grants only).

Coverage: 1986-present
Tags: Multidisciplinary

Norecopa, in collaboration with the Animal Welfare Information Center has produced a database which provides an overview of guidelines, databases, journals, email lists, regulations and policies which may help researchers to implement the 3Rs when planning research that may involve animals.

The 3Rs-Centre Utrecht Life Sciences (ULS) stimulates the development, acceptation and implementation of 3Rs methods (replacement, reduction and refinement of animal experiments). Two databases: the Interspecies Database (www.interspeciesinfo.com) and the Humane Endpoints website (www.humane-endpoints.info).

Alternatives Search Resources

The federal Animal Welfare Act requires that local institutional animal care and use committees (IACUCs) review certain local research protocols involving the use of animals. To assure a broad review, IACUCs include local members outside the animal care and research communities. As a result, IACUCs and research support staff become involved in the education of these members, their incorporation into committee problem solving, and in ethical decision making. This guide is intended to provide a brief list of resources on the functions and administration of institutional animal care and use committees, including these three areas. We invite your suggestions for additions and changes to this information guide.

UCDavis Institutional Animal Care and Use Committee

Publications

What animals want : expertise and advocacy in laboratory animal welfare policy
Carbone, Larry. Oxford ; New York : Oxford University Press, 2004.
Carlson Health Sci Library W20.55 A5 C27 2004
 .
The human use of animals : case studies in ethical choice
New York : Oxford University Press, 1998.
Carlson Health Sci Library W20.55 A5 H86 1998
.
Responsibility in the use of animals in bioscience research : Expectations of the major research council and charitable funding bodies
NC3Rs, BBSRC, MRC, NERC and Wellcome Trust.Sourcebook of models for biomedical research.  Totowa, N.J. : Humana Press, c2008.
Carlson Health Sci Library QY58 S724 2008
.
Laboratory animals in research and teaching : ethics, care, and methods
Washington, DC : American Psychological Association, c2005.
Carlson Health Sci Library QY50 L276 2005
.
The ethics of research involving animals
London : Nuffield Council on Bioethics, 2005.The design of animal experiments : reducing the use of animals in research through better experimental design.  London : Royal Society of Medicine, c2002.
Carlson Health Sci Library QY50 L22 no.14 2002
.
Animal training: a review and commentary on current practice
Proceedings of a symposium / organized by Universities Federation for Animal Welfare, held at the Peterhouse Theatre, University of Cambridge, 26th-27th September 1989.  Potters Bar, Herts, Eng. : Universities Federation for Animal Welfare, c1990.
Carlson Health Sci Library GV1829 A54 1990 Regular Loan
.
Education and training in the care and use of laboratory animals : A guide for developing institutional programs
Committee on Educational Programs in Laboratory Animal Science, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council. Washington, D.C. : National Academy Press, 1991.
.
.
“FELASA recommendations on the education and training of persons working with laboratory animals: categories A and C; Reports of the Federation of European Laboratory Animal Science Association’s Working Group on Education accepted by the FELASA Board of Management.”
Laboratory Animals. 1995; 29:121-31 (FELASA Guidelines)
.
Guidelines on the handling and training of laboratory animals prepared by the Biological Council Animal Research and Welfare Panel. Potters Bar. Universities Federation for Animal Welfare, 1992.
Carlson Health Sci Library SF406 G4 1992 Regular Loan
.
The UFAW Handbook on the Care and Management of Laboratory Animals, 7th edition. Editor T B Poole.  Two volumes, Volume 1 Terrestial vertebrates, Volume 2 Amphibious and aquatic vertebrates and advanced invertebrates. Blackwell Science 1999.
Carlson Health Sci Library QY50 U5 1999 Regular Loan
.

Searching Resources

Free Public Databases from NLM and NAL

Educational Alternatives Databases

Alternatives Search Guidelines (Complying with USDA Policies 11 and 12)

.
Literature Search
A minimum of two database searches that reflects a serious effort to address the “3Rs” (refinement, replacement, reduction) is required by federal law. It is also important to show that the proposed use of animals is not unnecessarily duplicative of other studies previously performed.

The 3Rs are:

  • Refinement of technique to reduce or eliminate unnecessary pain and distress an animal may experience.
  • Reduction, which refers to an effort to reduce the number of animals used overall within the study.
  • Replacement refers to replacing animals with non-animal alternatives, non-mammalian or invertebrate species.  Alternatives could include in vitro methods that utilize organ, tissue and cell culture, computer simulation models, microorganisms, plants, or chemical techniques.
Result of Search for Alternatives
Indicate the results of this search for alternatives, and whether you were able to identify alternatives that are included in the studies proposed. If no alternatives have been found, and if no prior studies have been performed that indicate duplication, then state this within the framework of the objectives of the study. It is important to state the unique aspects of your study in relation to the published literature. Please also include any procedures you have performed that indicate your efforts to decrease the use of animals. This could include in vitro studies or those performed with invertebrate or non-mammalian species. This helps document your efforts toward employing the concepts of the 3Rs.

Searching for alternatives means considering ways to reduce, refine, or replace whenever there is proposed animal use in research, teaching, or testing.  This guide will focus on the Animal Welfare Act (at left,…

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Database Approach to a Search

DATABASES BY ANIMAL MODEL

MODEL FREE DATABASES & RESOURCES LIBRARY DATABASES
animal model selection AGRICOLA
ILAR Journal issues
International Mouse Strain Resource
Mouse Models of Human Cancer
   Consortium
NIH Model Organisms
PubMed
PubMed Clinical Queries
AGRICOLA
Web of Science
PubMed 
mice AGRICOLA
AltBib
JAX Mice Database
Mouse Biology Program
PubMed
AGRICOLA
Web of Science
PubMed
fish/frogs/aquatic AGRICOLA
Fish and Wildlife Reference Service
FishBase
TOXNET
ZFIN
AGRICOLA
ASFA — Aquatic Sciences & Fisheries Abstracts
BIOSIS
large/farm animal, sheep, swine AGRICOLA
FASS Guide
PubMed
AGRICOLA
Animal Health & Production Compendium
CAB
non-human primates Guidelines for the Care & Use of Mammals
in Neuroscience & Behavioral Research
Primate Portal
PubMed
Web of Science
PsycInfo
PubMed
exotics WildPro Information Network BIOSIS
Wildlife & Ecology Studies Worldwide
Zoological Record
rats, guinea pigs, hamsters AGRICOLA
ANZCCART Fact Sheets
PubMed
AGRICOLA
PubMed
rabbits AGRICOLA
AWIC
PubMed
AGRICOLA
PubMed
dogs, cats AGRICOLA
PubMed
AGRICOLA
BIOSIS
Web of Science
PubMed

 

DATABASES BY TOPIC


TOPIC FREE DATABASES & RESOURCES
LIBRARY DATABASES
Husbandry AGRICOLA
AWI
Comfortable Quarters
NC3Rs Housing & Husbandry
UFAW
AGRICOLA
PsycInfo
Zoological Record
Behavior AGRICOLA
PubMed
UFAW
Web of Science
PsycInfo
Zoological Record
Euthanasia AVMA Guide
FASS Guide
PubMed
PubMed
Toxicity AnimalAlt-ZEBET
EcoTox
FRAME
ECVAM
ICCVAM
PubMed
TOXNET
Web of Science
PubMed
Tumors AGRICOLA
PubMed
UKCCCR Guidelines
AGRICOLA
PubMed
MAbs AGRICOLA
ECVAM Workshop
ILAR MAb Production
PubMed
AGRICOLA
PubMed
Teaching ERIC
NORINA
ERIC
CAB
Endpoints AVMA Euthanasia Guide
ILAR Journal ; ILAR Suppl
Laboratory Animals
PubMed
Web of Science
PubMed
Disease Models AGRICOLA
PubMed
AGRICOLA
Web of Science
PubMed
Emerging Technologies:
Imaging, Cell Culture
AnimalAlt-ZEBET
PubMed
BIOSIS
PubMed
Analgesia, Anesthesia AGRICOLA
AltWeb Refinement
PubMed
AGRICOLA
PubMed
Standard Care:
Transportation, Behavior,
Handling, Restraint, Identification
AGRICOLA
ANZCCART Fact Sheets
CCAC Policies & Guidelines
ILAR Lab Animal Care
PubMed
NC3Rs Blood Sampling
Microsite
AGRICOLA
PubMed
UC Davis Policies
& Guidelines

 Databases by Species/Model: Identifying potential models

Interspecies Database

Animal Model Selection : Potential Models

 

Free Databases

AGRICOLA
AltBib
DTIC
ECVAM
ECOTOX
FishBase
ICCVAM
JAX
NCBI
PrimateLit
PubMed
RePORTER
TOXNET
WildPro
ZFin

Free Resources

Humane Endpoints
ANZCCART Fact Sheet:Pain
Ensembl Genome Browser
ILAR Animal Models
Intern’l Mouse Strain Resource
Mouse Genome Informatics
Mouse Models of Human-Cancers
   Consortium
NCI Mouse Models
NIH Model Organisms
UKCCCR Guidelines
NIGMS Trauma, Burn, Wound

Suggested Library Databases

ASFA
Biosis
CAB
Embase
ERIC
Fish, Fisheries & Aquatic
   Biodiversity Worldwide
ISI Web of Science
PsycInfo
RTECS
SciFinder
Wildlife & Ecology Studies
Worldwide
Zoological Record

FREE DATABASES LIBRARY DATABASES EMBEDDED SEARCHES
rats, guinea pigs, hamsters, rabbits, ferrets
AGRICOLA
PubMed
ANZCCART Fact Sheets
Biosis
Web of Science
ferrets & helicobacter
gp & hyperlipidemia
gp & osteoarthritisrats &
wound healing
rats & encephalomyelitis
rabbits & thrombosis
exotics
WildPro Information Network
ANZCCART Fact Sheet
Biosis
Wildlife & Ecology Studies Worldwide
Zoological Record
as model
farm animals
AGRICOLA
PubMed
Animal Health &Production Compen
Biosis
CAB
FASS Guide
ISI Web of Science
cattle as model
chickens as model
dogs, cats
AGRICOLA
PubMed
ANZCCART Fact Sheet
Biosis
CAB
ISI Web of Science
sleep apnea
sea urchin embryo
PubMed
TOXNET
ASFA
Biosis
SciFinder
cellular activity
metals & early development

transcription
in TOXLINE
in
HSDB
S. cerevisiae (budding yeast)
PubMed Biosis
Web of Science
drug design
glucose
DNA
neurospora (filamentous fungus)
PubMed Biosis model
evolutionary
D. discoideum (social amoebae)
PubMed
DictyBase
NIH Resources
Biosis
Web of Science
cytokinesis
signal transduction
development
C. elegans (round worm)
PubMed
WormBase
Biosis
Web of Science
aging
neurological model
D. melanogaster (fruit fly)
PubMed
Flybase
Biosis
Web of Science
hearing
balance
neurodegenerative model
aging
bees
PubMed Biosis
Web of Science
ethanol/alcohol
fish / frogs / aquatic
AGRICOLA
PubMed
TOXNET
FishBase
Xenopus Resources
Zebrafish Gene Collection
ZFIN
ASFA
Biosis
Fish and Fisheries Worldwide
Zoological Record
zfish as model
zfish & obesity/diabetes
frogs & oncogenesis
frogs & neurogenesis
mice
AGRICOLA
AltBib
PubMed
JAX Mouse Genome Informatics
Mouse Biology Program
Biosis
Web of Science
as model
A
lzheimers
obesity
non-human primates
PrimateLit
PubMed
Guidelines for the Care & Use of
Mammals  in Neuroscience
Behavioral Research
Biosis
Web of Science
PsycInfo
as model
HIV vaccine