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This guide provides an overview of evidence-based practice resources. Includes: point of care resources, systematic reviews, clinical practice guidelines, literature databases, and background sources.

VPN log-in is required for off-campus or guest wifi access to these resources, except where noted [Free].

Amy Studer

Blaisdell Medical Library
Medicine

acstuder@ucdavis.edu

916-734-0206

In this Guide:

JAMA Evidence provides online access to key evidence-based medicine resources, in particular “Users’ Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice” and “The Rational Clinical Examination: Evidence-Based Clinical Diagnosis“.

Also included are calculators, audio clips, learning tools, education guides, and critical appraisal worksheets.

More than 28 million citations and abstracts for articles published in approximately 8,400 journals in medicine, life sciences, health administration, veterinary medicine, nursing, molecular biology and genetics. PubMed is a service of the U.S. National Library of Medicine on the NCBI platform.

PubMed Tutorial & more
Alerts/Automatic Updating Service (Saving & Managing Searches)
NLM Searching PubMed with Mesh tri-fold handout [PDF]
NLM PubMed Basics tri-fold handout [PDF]

Coverage: 1946-present
Tags: Animals, Dentistry, Medicine, Nursing, Veterinary Medicine
Related links: PubMed mobile PICO interface

References and abstracts on nursing, biomedical, allied health and consumer health literature. Also includes health care books, nursing dissertations, selected conference proceedings, standards of practice, educational software, audiovisuals and book chapters, as well as Evidence-Based care sheets. Full text is provided for hundreds of journals, plus legal cases, clinical innovations, critical paths, drug records, research instruments and clinical trials. Includes PreCINAHL as a companion database.

Coverage: -1982
Tags: Allied Health, Forensics, Medicine, Nursing

PsycINFO is a department of the American Psychological Association (APA). It provides citations to articles in professional journals, conference proceedings, books, reports, dissertations and even important internet sites in psychology and related disciplines, most with abstracts and some citations.

Coverage: 1840-present
Tags: Psychology

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Large interdisciplinary abstract and citiation database to academic journal literature, conference proceedings and books with broad coverage across the sciences and social sciences, includes citation tracking tools.

Coverage: full coverage from 1996-present, with selected coverage as far back as 1823
Tags: Art, Biology, Humanities, Multidisciplinary, Science, Social Science

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Embase is a biomedical and pharmacological database containing bibliographic records with citations, abstracts and indexing derived from biomedical articles in peer reviewed journals, and is especially strong in its coverage of drug and pharmaceutical research and conference abstracts.Embase contains over 22 million records spanning 1974-present, with over 1 million records added annually. Each record contains the full bibliographic citation, indexing terms, and codes; and 80% of all citations in Embase include author-written abstracts. The Embase journal collection is international with over 7,500 active peer-reviewed journals more than 90 countries. All MEDLINE records produced by the National Library of Medicine (NLM) are included, as well as over 5 million records not covered in MEDLINE. Broad biomedical scope covering the following areas:

  • Drug therapy and research, including pharmaceutics, pharmacology and toxicology
  • Clinical and experimental (human) medicine
  • Basic biological science relevant to human medicine
  • Biotechnology and biomedical engineering, including medical devices
  • Health policy and management, including pharmacoeconomics
  • Public, occupational and environmental health, including pollution control
  • Veterinary science, dentistry, and nursing
  • Psychiatry and mental health, including substance dependence and abuse
  • Forensic science
  • Alternative and complementary medicine
Coverage: 1974-current (for EMBASE records); 1966-current (for MEDLINE records)
Tags: Allied Health, Medicine, Nursing, Public Health
Related links: Embase PICO search,

The Ovid interface to MEDLINE.Citations and abstracts for articles published in approximately 8,400 journals in medicine, life sciences, health administration, veterinary medicine, nursing, molecular biology and genetics. MEDLINE is a service of the U.S. National Library of Medicine.

Coverage: 1948-present
Tags: Dentistry, Medicine, Nursing, Public Health, Veterinary Medicine
Related links: Ovid MEDLINE PICO search,

Web of Science combines traditional bibliographic searching of journal content across the humanities, social sciences, and natural sciences with broadly interdisciplinary “cited reference” search capabilities.

Quick Reference Guide: Web of Science Core Collection
Saving Your Search & Setting Alerts
Creating Citation Alerts for Current Awareness

Coverage: See above description (varies between 9 indexes)
Tags: Science

The Clinical Resources Center (CRC) is the portal to information resources for clinicians at UC Davis Health. A collaboration of the UC Davis Center for Health Technology and the UC Davis Library, it is hosted by the UC Davis School of Medicine.

The CRC also provides customized content for first and third year medical students.

Access from off-campus requires login with Pulse Secure.

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DynaMed is a point-of-care clinical medicine database that is updated multiple times each day. DynaMed integrates drug information, graphics/images, and levels of evidence labels. The University of California began a 2 year trial of Dynamed in June 2018.

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UpToDate is a point-of-care clinical medicine database, providing coverage of over 8500 topics in 17 medical specialties. UpToDate integrates drug information (Lexi-Comp) and clinical images (Visual Dx).

MicroMedex Health enables searching across a suite of drug information databases, covering drug administration, adverse effects, clinical applications, contraindications, dosage, indications, interactions, over-dosage, pharmacology, precautions, product/substance identification, toxicity, references, synonyms, and uses. Databases include: NeoFax, Physicians Desk Reference (PDR), Martindale International drug information – including investigational and herbal drugs, POISINDEX, and DRUGDEX (Consults and Evaluations), P&T Quik Reports, MSDS from USP, REPRORISK, DESEASEDEX (General and Emergency), Alternative Medicines, TOMES, and RED BOOK (wholesale drug prices) .

Coverage: varies
Tags: Alternative Medicine, Diseases, Medicine, Poisons

Essential Evidence Plus offers a system of filtered, synopsized, evidence-based information, with an integrated search engine that enables simultaneous keyword search in multiple databases: Essential Evidence Topics, EBM Guidelines, POEMs Research Summaries, Cochrane Systematic Reviews, NGC Practice Guidelines, Decision Support Tools, H&P Calculators, Diagnostic Test Calculators, Derm Expert Image Viewer, and Medicare’s Evaluation & Management Services Coding.

Tags: Medicine

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VisualDx is a web-based clinical decision support system proven to enhance diagnostic accuracy, aid therapeutic decisions, and improve patient safety and is based on images of the physical exam. It includes the Differential Builder, which provides a symptom based approach to diagnosis.

Natural Medicines provides clinical, evidence-based information on dietary supplements, natural medicines, and complementary, alternative, and integrative therapies.  Search results in Natural Medicines draw from several databases: Foods, Herbs & Supplements; Health & Wellness; Comparative Effectiveness; Sports Medicine; Medical conditions; Manufacturers; and, Commercial Products. Special tools provide quick guidance about: interactions, nutrition depletion, effectiveness, adverse effects, and pregnancy & lactation. Natural Medicines merges content from the former Natural Standard and Natural Medicines Comprehensive Database.

The TDS Health platform (formerly STAT!Ref, aka StatRef) provides access to point-of care-tools, including Decker Medicine, Decker Surgery, and EBMcalc, a clinical decision support tool. The STAT!Ref platform offers access to the latest editions of selected medical and pharmacological ebooks (e.g., AJCC Cancer Staging Manual, Trissel’s Stability of Compound Formulations, Handbook on Injectable Drugs), dictionaries (e.g., Stedman’s Medical DictionaryDorland’s Dictionary of Medical Acronyms) and indexes. Other features include consumer health resources and patient handouts (e.g., AAFP Conditions, Merck Manual), medical ICD-10 coding resources and Reuter’s medical news feeds.

Users are able to cross-search the entire library and results are displayed as hot links leading to detailed information in full-text book format with tables and graphics. A mobile app is available — requires creating a free individual account (instructions posted on the STAT!Ref website).

 



What is a systematic review?

Institute of Medicine (2011): “A scientific investigation that focuses on a specific question and uses explicit, planned scientific methods to identify, select, assess, and summarize the findings of similar but separate studies. It may or may not include a quantitative synthesis of the results from separate studies (meta-analysis).”

Cochrane: “A systematic review summarises the results of available carefully designed healthcare studies (controlled trials) and provides a high level of evidence on the effectiveness of healthcare interventions. Judgments may be made about the evidence and inform recommendations for healthcare.”

The Cochrane Database of Systematic Reviews is an important resources for high quality systematic reviews in health care, including all reviews and protocols prepared by Cochrane Review Groups. Each Cochrane Review is a peer-reviewed systematic review that has been prepared and supervised by a Cochrane Review Group (editorial team), and prepared according to the Cochrane Handbook for Systematic Reviews of Interventions or Cochrane Handbook for Diagnostic Test Accuracy Reviews.

Cochrane Systematic Reviews are also discoverable in PubMed, Essential Evidence Plus, and TRIP Pro.

 

The Joanna Briggs Institute, an international not-for-profit research and development organization, develops evidence for nursing, allied health, and medical professionals, as well as healthcare consumers. Systematic reviews in JBI EBP Database complement those found in the Cochrane Library. Includes: Evidence Summaries — Literature reviews that summarize existing international literature on common healthcare interventions and activities; Evidence-Based Recommended Practices — Database of procedures that describe and/or recommend practice on various clinical topics; Best Practice Information Sheets — Series of information guideline sheets produced specifically for practicing health professionals; Systematic Reviews — Comprehensive systematic reviews of international research literature completed by trained JBI reviewers; Consumer Information Sheets — Standardized summaries designed just for consumers of healthcare (patients, clients, and care providers); Systematic Review Protocols — Developed by the Collaborating Centers of JBI, which are made up of international experts from over 40 countries from a range of health disciplines; and, Technical Reports — Documentation of all aspects of the development of Best Practice Information Sheets.

 

Accessible from the PubMed homepage, Clinical Queries utilizes search filters designed to retrieve systematic reviews, meta-analyses, practice guidelines, clinical trials, and human medical genetics-related articles.  Clinical trials results can be customized based on PICO search categories: etiology, diagnosis, therapy, prognosis, and clinical prediction guides.

TRIP Database (Turning Research Into Practice) is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care. Categories searched by the TRIP Database include: evidence based synopses; systematic reviews; guidelines (US & UK); fore primary research; and patient information.

The “Locating Systematic Reviews” section of this library guide will direct you to systematic review databases for various health science disciplines, such as: Campbell Collaboration, DARE, DoPHER, EPPI-Centre, OTseeker, PEDro, PsycBITE, SpeechBite, VetSRev.

In addition to the sources below, many professional organizations publish clinical practice guidelines on their websites (e.g. ACP, AAFP).

Provides complete titles of released evidence reports, comparative effectiveness reviews, technical briefs, Technology Assessment Program reports, and U.S. Preventive Services Task Force evidence syntheses. These reports may be used for informing and developing coverage decisions, quality measures, educational materials and tools, clinical practice guidelines, and research agendas.

Users must first register for a free personal account to access ECRI Guidelines Trust content from the ECRI Institute website. The ECRI Guidelines Trust provides free access to a subset of information that is available from ECRI Institute.

“ECRI Guidelines Trust TM is a publicly available web-based repository of objective, evidence-based clinical practice guideline content. Its purpose is to provide physicians, nurses, other clinical specialties, and members of the healthcare community with up-to-date clinical practices to advance safe and effective patient care. This centralized repository includes evidence-based guidance developed by nationally and internationally recognized medical organizations and medical specialty societies.” In addition to clinical practice guidelines, content includes Guideline Briefs and TRUST Scorecards. Source: About ECRI Guidelines Trust

 

Accessible from the PubMed homepage, Clinical Queries utilizes search filters designed to retrieve systematic reviews, meta-analyses, practice guidelines, clinical trials, and human medical genetics-related articles.  Clinical trials results can be customized based on PICO search categories: etiology, diagnosis, therapy, prognosis, and clinical prediction guides.

TRIP Database (Turning Research Into Practice) is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care. Categories searched by the TRIP Database include: evidence based synopses; systematic reviews; guidelines (US & UK); fore primary research; and patient information.

Background resources provide an overview of a disease or condition, including what is generally known and accepted.  Common examples include textbooks or peer-reviewed review articles on a topic.  It is important to note the publication date and currency of references.

Filter PubMed search results by “review” article in left pre-set filters.

AccessMedicine is an online platform for a collection of core medical eBooks and test preparation resources from McGraw Hill.

This guide offers a selected list of health sciences eBooks available through UC Davis Library.

Library Search is the new UC Davis Library catalog search tool.

This online resource presents key studies that have shaped the practice of medicine. Selected using a rigorous methodology, it covers topics including dieting, cardiovascular disease, insomnia, obstetrics, and more. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. Brief information on other relevant studies is provided, and an illustrative clinical case concludes each review. A section of review questions and answers is included to ensure that readers take away the key messages from each study.