This guide provides an overview of evidence-based practice resources, using the levels of evidence pyramid as a  framework. Includes: point of care resources, systematic reviews, clinical practice guidelines, literature databases, and background sources.

VPN log-in is required for off-campus or guest wifi access to these resources, except where noted [Free].

Amy Studer

Blaisdell Medical Library
Health & Life Science Librarian

acstuder@ucdavis.edu

916-734-0206

In this Guide:

Background resources provide an overview of a disease or condition, including what is generally known and accepted.  Common examples include textbooks or peer-reviewed review articles on a topic.  It is important to note the publication date and currency of references.

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More than 27 million citations and abstracts for articles published in approximately 8,400 journals in medicine, life sciences, health administration, veterinary medicine, nursing, molecular biology and genetics. PubMed is a service of the U.S. National Library of Medicine on the NCBI platform.

PubMed Tutorial & more
Alerts/Automatic Updating Service (Saving & Managing Searches)
NLM Searching PubMed with Mesh tri-fold handout [PDF]
NLM PubMed Basics tri-fold handout [PDF]

Coverage: 1946-present
Tags: Animals, Dentistry, Medicine, Nursing, Veterinary Medicine

References and abstracts on nursing, biomedical, allied health and consumer health literature. Also includes health care books, nursing dissertations, selected conference proceedings, standards of practice, educational software, audiovisuals and book chapters, as well as Evidence-Based care sheets. Full text is provided for hundreds of journals, plus legal cases, clinical innovations, critical paths, drug records, research instruments and clinical trials. Includes PreCINAHL as a companion database.

Coverage: -1982
Tags: Allied Health, Forensics, Medicine, Nursing

PsycINFO is a department of the American Psychological Association (APA). It provides citations to articles in professional journals, conference proceedings, books, reports, dissertations and even important internet sites in psychology and related disciplines, most with abstracts and some citations.

Coverage: 1840-present
Tags: Psychology

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Large interdisciplinary abstract and citiation database to academic journal literature, conference proceedings and books with broad coverage across the sciences and social sciences, includes citation tracking tools.

Coverage: full coverage from 1996-present, with selected coverage as far back as 1823
Tags: Art, Biology, Humanities, Multidisciplinary, Science, Social Science

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Embase is a biomedical and pharmacological database containing bibliographic records with citations, abstracts and indexing derived from biomedical articles in peer reviewed journals, and is especially strong in its coverage of drug and pharmaceutical research and conference abstracts.Embase contains over 22 million records spanning 1974-present, with over 1 million records added annually. Each record contains the full bibliographic citation, indexing terms, and codes; and 80% of all citations in Embase include author-written abstracts. The Embase journal collection is international with over 7,500 active peer-reviewed journals more than 90 countries. All MEDLINE records produced by the National Library of Medicine (NLM) are included, as well as over 5 million records not covered in MEDLINE. Broad biomedical scope covering the following areas:

  • Drug therapy and research, including pharmaceutics, pharmacology and toxicology
  • Clinical and experimental (human) medicine
  • Basic biological science relevant to human medicine
  • Biotechnology and biomedical engineering, including medical devices
  • Health policy and management, including pharmacoeconomics
  • Public, occupational and environmental health, including pollution control
  • Veterinary science, dentistry, and nursing
  • Psychiatry and mental health, including substance dependence and abuse
  • Forensic science
  • Alternative and complementary medicine
Coverage: 1974-current (for EMBASE records); 1966-current (for MEDLINE records)
Tags: Allied Health, Medicine, Nursing, Public Health

The Ovid interface to MEDLINE.Citations and abstracts for articles published in approximately 8,400 journals in medicine, life sciences, health administration, veterinary medicine, nursing, molecular biology and genetics. MEDLINE is a service of the U.S. National Library of Medicine.

Coverage: 1948-present
Tags: Dentistry, Medicine, Nursing, Public Health, Veterinary Medicine

Web of Science combines traditional bibliographic searching of journal content across the humanities, social sciences, and natural sciences with broadly interdisciplinary “cited reference” search capabilities.

Quick Reference Guide: Web of Science Core Collection
Saving Your Search & Setting Alerts
Creating Citation Alerts for Current Awareness

Coverage: See above description (varies between 9 indexes)
Tags: Science

Essential Evidence Plus offers a system of filtered, synopsized, evidence-based information, with an integrated search engine that enables simultaneous keyword search in multiple databases: Essential Evidence Topics, EBM Guidelines, POEMs Research Summaries, Cochrane Systematic Reviews, NGC Practice Guidelines, Decision Support Tools, H&P Calculators, Diagnostic Test Calculators, Derm Expert Image Viewer, and Medicare’s Evaluation & Management Services Coding.

Tags: Medicine

MicroMedex Health enables searching across a suite of drug information databases, covering drug administration, adverse effects, clinical applications, contraindications, dosage, indications, interactions, over-dosage, pharmacology, precautions, product/substance identification, toxicity, references, synonyms, and uses. Databases include: NeoFax, Physicians Desk Reference (PDR), Martindale International drug information – including investigational and herbal drugs, POISINDEX, and DRUGDEX (Consults and Evaluations), P&T Quik Reports, MSDS from USP, REPRORISK, DESEASEDEX (General and Emergency), Alternative Medicines, TOMES, and RED BOOK (wholesale drug prices) .

Coverage: varies
Tags: Alternative Medicine, Diseases, Medicine, Poisons

Natural Medicines provides clinical, evidence-based information on dietary supplements, natural medicines, and complementary, alternative, and integrative therapies. Search results in Natural Medicines draw from several databases: Foods, Herbs & Supplements; Health & Wellness; Comparative Effectiveness; Sports Medicine; Medical conditions; Manufacturers; and, Commercial Products. Special tools provide quick guidance about: interactions, nutrition depletion, effectiveness, adverse effects, and pregnancy & lactation. Natural Medicines merges content from the former Natural Standard and Natural Medicines Comprehensive Database.

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UpToDate is a point-of-care clinical medicine database, providing coverage of over 8500 topics in 17 medical specialties. UpToDate integrates drug information (Lexi-Comp) and clinical images (Visual Dx).

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VisualDx is a web-based clinical decision support system proven to enhance diagnostic accuracy, aid therapeutic decisions, and improve patient safety and is based on images of the physical exam. It includes the Differential Builder, which provides a symptom based approach to diagnosis.



The Cochrane Database of Systematic Reviews is an important resources for high quality systematic reviews in health care, including all reviews and protocols prepared by Cochrane Review Groups. Each Cochrane Review is a peer-reviewed systematic review that has been prepared and supervised by a Cochrane Review Group (editorial team), and prepared according to the Cochrane Handbook for Systematic Reviews of Interventions or Cochrane Handbook for Diagnostic Test Accuracy Reviews.

Cochrane Systematic Reviews are also discoverable in PubMed, Essential Evidence Plus, and TRIP Pro.

 

The Joanna Briggs Institute, an international not-for-profit research and development organization, develops evidence for nursing, allied health, and medical professionals, as well as healthcare consumers. Systematic reviews in JBI EBP Database complement those found in the Cochrane Library. Includes: Evidence Summaries — Literature reviews that summarize existing international literature on common healthcare interventions and activities; Evidence-Based Recommended Practices — Database of procedures that describe and/or recommend practice on various clinical topics; Best Practice Information Sheets — Series of information guideline sheets produced specifically for practicing health professionals; Systematic Reviews — Comprehensive systematic reviews of international research literature completed by trained JBI reviewers; Consumer Information Sheets — Standardized summaries designed just for consumers of healthcare (patients, clients, and care providers); Systematic Review Protocols — Developed by the Collaborating Centers of JBI, which are made up of international experts from over 40 countries from a range of health disciplines; and, Technical Reports — Documentation of all aspects of the development of Best Practice Information Sheets.

 

Accessible from the PubMed homepage, Clinical Queries utilizes search filters designed to retrieve systematic reviews, meta-analyses, practice guidelines, clinical trials, and human medical genetics-related articles.  Clinical trials results can be customized based on PICO search categories: etiology, diagnosis, therapy, prognosis, and clinical prediction guides.

A curated database of systematic reviews, clinical guidelines, and health technology assessment executive summaries. Links to PubMed systematic review filter and systematic review methods literature.

TRIP Database (Turning Research Into Practice) is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care. Categories searched by the TRIP Database include: evidence based synopses; systematic reviews; guidelines (US & UK); fore primary research; and patient information.

More health science discipline-specific systematic review databases

This webpage will direct you to systematic review databases for various health science disciplines, such as: Campbell Collaboration, DARE, DoPHER, EPPI-Centre, OTseeker, PEDro, PsycBITE, SpeechBite, VetSRev.

In addition to the sources below, many professional organizations publish clinical practice guidelines on their websites (e.g. ACP, AAFP).

NGC is an initiative of the Agency for Healthcare Research and Quality (AHRQ), whose mission is to provide physicians and other health professionals, health care providers, health plans, integrated delivery systems, purchasers, and others an accessible mechanism for obtaining objective, detailed information on clinical practice guidelines and to further their dissemination, implementation, and use.

Provides complete titles of released evidence reports, comparative effectiveness reviews, technical briefs, Technology Assessment Program reports, and U.S. Preventive Services Task Force evidence syntheses. These reports may be used for informing and developing coverage decisions, quality measures, educational materials and tools, clinical practice guidelines, and research agendas.

Accessible from the PubMed homepage, Clinical Queries utilizes search filters designed to retrieve systematic reviews, meta-analyses, practice guidelines, clinical trials, and human medical genetics-related articles.  Clinical trials results can be customized based on PICO search categories: etiology, diagnosis, therapy, prognosis, and clinical prediction guides.

A curated database of systematic reviews, clinical guidelines, and health technology assessment executive summaries. Links to PubMed systematic review filter and systematic review methods literature.

TRIP Database (Turning Research Into Practice) is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care. Categories searched by the TRIP Database include: evidence based synopses; systematic reviews; guidelines (US & UK); fore primary research; and patient information.

EBMG Guidelines is a unique, concise and easy-to-use collection of clinical guidelines for primary care.

Background resources provide an overview of a disease or condition, including what is generally known and accepted.  Common examples include textbooks or peer-reviewed review articles on a topic.  It is important to note the publication date and currency of references.

Filter PubMed search results by “review” article in left pre-set filters.

AccessMedicine is an online platform for a collection of core medical eBooks and test preparation resources from McGraw Hill.

This guide offers a selected list of health sciences eBooks available through UC Davis Library.

Library Search is the new UC Davis Library catalog search tool.

Thanks to Raquel Ramirez for help with migrating and developing this web content.